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Table 1 General characteristics of the study population (nā€‰=ā€‰896)

From: Fresh or frozen day 6 blastocyst transfer: is there still a question?

Ā 

D6 frozen blastocyst transfers

(nā€‰=ā€‰787)

D6 fresh blastocyst transfers

(nā€‰=ā€‰109)

P-value

Mean age at retrieval (y.o.)

36.1Ā Ā±Ā 4.1

35.9Ā Ā±Ā 4.4

0.966 mw

Smoking habits (%)

82 (10.4)

14 (12.8)

0.442k

BMI (kg/m2)

23.6

23.8

0.485 mw

Type of infertility

Ā Ā 

0.123k

Primary

528 (67.1)

65 (59.6)

Ā 

Secondary

259 (32.9)

44 (40.4)

Ā 

Main causes of infertility*

Ā Ā Ā 

Endometriosis

346 (44.0)

38 (34.9)

0.072k

Male factor

299 (38.0)

48 (44.0)

0.225k

Tubal factor

145 (18.4)

12 (11.0)

0.056k

Ovulatory disorders

48 (6.1)

3 (2.8)

0.158k

Idiopathic

70 (8.9)

13 (11.9)

0.309k

Ovarian reserve

Ā Ā Ā 

Day 3 FSH (IU/L)

7.1Ā Ā±Ā 2.3

7.6Ā Ā±Ā 2.9

0.132 mw

Day 3 estradiol (pg/mL)

51.1Ā Ā±Ā 84.3

47.1Ā Ā±Ā 19.2

0.349 mw

AMH (ng/mL)

2.8Ā Ā±Ā 2.2

1.8Ā Ā±Ā 1.4

<Ā 0.001 mw

AFC (mean)

17.1Ā Ā±Ā 10.8

13.9Ā Ā±Ā 7.5

0.006 mw

IVF/ICSI rank (n)

1.6Ā Ā±Ā 1.1

1.9Ā Ā±Ā 1.1

<Ā 0.001 mw

Endometrial thickness (mm)

9.0Ā Ā±Ā 1.9

9.4Ā Ā±Ā 2.6

0.035 mw

Top- or good-quality embryo transfera

542 (68.9)

82 (75.2)

0.176k

Top-quality embryoa

26 (3.3)

0 (0.0)

0.054k

Type of endometrial preparation (FET cycle only) (%)

Ā Ā 

NA

HRT cycle

547 (69.6)

NA

Ā 

HRT cycleā€‰+ā€‰downregulation with GnRHa

152 (19.3)

NA

Ā 

Natural cycle

72 (9.1)

NA

Ā 

Stimulated cycle

16 (2.0)

NA

Ā 
  1. D6 blastocystā€‰=ā€‰day 6 blastocyst; y.o., years old; IVF/ICSI, in vitro fertilization/intracytoplasmic sperm injection; AFC, antral follicle count; AMH, anti-MĆ¼llerian hormone; BMI, body mass index; FET, frozen embryo transfer; FSH, follicle-stimulating hormone; HRT, hormonal replacement therapy
  2. *Several associated infertility causes for some patients
  3. a ā€“ A top-quality embryo was defined as a B3ā€“B4 or B5 embryoĀ =Ā AA, and a good-quality embryo was defined as a B3ā€“B4 or B5 embryo ā‰„Ā BB (AB, BA, or BB) according to the grading scale proposed by Gardner; *Couples can have several causes of infertility
  4. The data are presented as meansā€‰Ā±ā€‰the standard error or n (%) unless specified otherwise. mw Mannā€“Whitney t-test; k Pearsonā€™s chi-square test