Body mass index impacts ectopic pregnancy during in vitro fertilization: an analysis of 42,362 clinical pregnancy cycles

Table 4 Multivariate logistic regression analysis of risk factors for ectopic pregnancy

	Fresh embryo transfer		Frozen-thawed embryo transfer
	Adjusted OR (95% CI)	P	Adjusted OR (95% CI)	P
BMI (kg/m²)
< 18.5	Reference		Reference
18.5–23.9	0.98 (0.70–1.37)	0.894	1.15 (0.89–2.05)	0.513
≥ 24	0.89 (0.75–1.06)	0.205	1.24 (0.94–2.65)	0.367
Infertility type			/
Primary	Reference		/
Secondary	1.19 (1.02–1.40)	0.032	/
Tubal factor existed
Yes	1.57 (1.24–2.58)	0.017	1.32 (0.87–1.93)	0.081
No	Reference		Reference
Peak Estrogen level (pg/ml)			/
< 2500	Reference		/
[2500–5000)	1.04 (0.86–1.25)	0.686	/
[5000–7500)	1.38 (1.08–1.75)	0.009	/
≥ 7500	1.75 (1.27–2.39)	0.001	/
Endometrial thickness (mm)
Thin (< 7)	3.04 (1.88–4.93)	< 0.001	5.10 (2.33–10.17)	0.000
Medium (8–13)	1.50 (1.24–1.81)	< 0.001	2.14 (1.09–4.18)	0.027
Thick (≥ 14)	Reference		Reference
Type of embryos
Cleavage	1.62 (1.09–2.42)	0.018	1.63 (1.13–2.33)	0.008
Blastocyst	Reference		Reference
No. of embryos transferred
1	Reference		Reference
2	1.22 (0.58–2.57)	0.602	1.24 (0.83–2.96)	0.291
3	1.31 (0.67–2.55)	0.432	1.47 (0.96–3.41)	0.072

Note BMI, body mass index; OR, odds ratio; CI, confidence interval
In fresh cycles, adjusted factors were BMI, infertility type, tubal factor, peak estrogen level, endometrial thickness, type of embryos, and number of embryos transferred. In frozen thawed cycles, adjusted factors were BMI, tubal factor, endometrial thickness, type of embryos, and number of embryos transferred

ISSN: 1477-7827