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Table 1 Examples of queries raised by group members. FP-fertility preservation. POI-premature ovarian insufficiency

From: What are the most common controversial clinical issues in fertility preservation? A content analysis of a collaborative professional online consultation group

Oncofertility cases (30%),

 • 16.5 y.o. with Hodgkin’s disease. planned to receive 2.5 gr of cyclophosphamide. Oncologist against FP. Should we offer FP?

 • 28 y.o. single male. Stage IV Hodgkin’s disease with superior vena cava syndrome. Very few immotile sperm cell in ejaculate. Should we attain testicular sperm?

Potential gonadotoxic damage of various medical treatments (23%)

 • Is FP indicated in a patient with carcinoma of thyroid prior to radiotherapy?

 • 23 y.o. stage IV clear cell carcinoma of kidney, planned to receive Lenvatinib plus Pembrolizumab. Should we offer FP?

Women and girls with POI (16%)

 • 14 y.o. family history of POI (mother & aunt), AMH 0.6, no genetic diagnosis. Should we offer FP?

 • 12.5 y.o.Turner mosaicism, low ovarian reserve markers. What to do?

Ovarian tissue cryopreservation (9%)

 • how long can we keep ovarian tissue in media prior to freezing?