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Table 2 Pregnancy Outcomes of MZT for different ART methods

From: Pregnancy and neonatal outcomes of monozygotic twins resulting from assisted reproductive technology: a 10-year retrospective study

Pregnancy Outcome

IVF, n = 71

ICSI, n = 35

PGT, n = 66

TESA, n = 15

χ2/R2

P value

    

Live births

43/71(60.5%)

31/35(88.5%)

51/66(77.2%)

12/15(80%)

10.92

0.012

    

Preterm births

16/71(22.5%)

12/35(34.3%)

24/66(36.4%)

5/15(33.3%)

3.49

0.322

    

Full-term births

27/71(38.0%)

19/35(54.3%)

27/66(41.0%)

7/15(46.7%)

2.74

0.434

    

Pregnancy days*

248.5(21.9)

251.0(15.0)

256.3(15.1)

259.9(18.7)

0.05

0.090

    

Caesarean deliveries

33/43(76.7%)

27/31(87.1%)

48/51(94.1%)

10/12(83.3%)

5.99

0.112

    

Spontaneous fetal reduction

12/43(27.9%)

4/31(12.9%)

14/51(27.5%)

5/12(41.7%)

4.47

0.215

    

Fetal reduction by surgery

1/43(2.3%)

0/31(0%)

2/51(3.9%)

0/12(0%)

1.68

0.641

    

Pregnancy losses

28/71(39.4%)

4/35(11.4%)

15/66(22.7%)

3/15(20%)

10.92

0.012

    

 Early miscarriages

21/71(29.5%)

3/35(8.5%)

11/66(16.6%)

2/15(13.3%)

7.86

0.049

    

 Late miscarriages

6/71(8.4%)

1/35(2.8%)

4/66(6.0%)

1/15(6.6%)

1.24

0.743

    

Pregnancy complications #

    

IVF/ICSI

P value

IVF/PGT

P value

IVF/TESA

P value

ICSI/PGT

P value

ICSI/TESA

P value

PGT/TESA

P value

 TTTS

2/71(2.8%)

0/35(0%)

0/66(0%)

3/15(20%)

> 0.999

0.497

0.353

> 0.999

0.023

0.005

 sIUGR

3/71(4.2%)

1/35(2.9%)

2/66(3.0%)

0/15(0%)

> 0.999

> 0.999

> 0.999

> 0.999

> 0.999

> 0.999

 PPROM

7/71(9.9%)

7/35(20%)

6/66(9.0%)

1/15(6.7%)

0.221

> 0.999

> 0.999

0.132

0.407

> 0.999

 GH

2/71(2.8%)

2/35(5.7%)

5/66(7.6%)

0/15(0%)

0.597

0.262

> 0.999

> 0.999

> 0.999

0.578

 GDM

2/71(2.8%)

4/35(11.4%)

7/66(10.6%)

1/15(6.7%)

0.091

0.088

0.442

> 0.999

> 0.999

> 0.999

 OH

1/71(1.4%)

0/35(0%)

1/66(1.5%)

0/15(0%)

> 0.999

> 0.999

> 0.999

> 0.999

> 0.999

> 0.999

 HT

0/71(0%)

1/35(2.9%)

0/66(0%)

0/15(0%)

0.330

> 0.999

> 0.999

0.347

> 0.999

> 0.999

 ICP

0/71(0%)

1/35(2.9%)

0/66(0%)

0/15(0%)

0.330

> 0.999

> 0.999

0.347

> 0.999

> 0.999

 Anemia

1/71(1.4%)

2/35(5.7%)

2/66(3.0%)

0/15(0%)

0.253

0.609

> 0.999

0.608

> 0.999

> 0.999

 Fetal distress

0/71(0%)

0/35(0%)

2/66(3.0%)

1/15(6.7%)

> 0.999

0.227

0.174

0.540

0.300

0.468

 Thrombocytopenia

1/71(1.4%)

0/35(0%)

0/66(0%)

0/15(0%)

> 0.999

> 0.999

> 0.999

> 0.999

> 0.999

> 0.999

 Thromboembolism

0/71(0%)

0/35(0%)

1/66(1.5%)

0/15(0%)

> 0.999

0.482

> 0.999

> 0.999

> 0.999

> 0.999

  1. Data presented as n (%), data* presented as the mean (SD). Data# analyzed using the Fisher’s exact test and the Bonferroni correction. TTTS, Twin-to-twin transfusion syndrome; sIUGR, Selective intrauterine growth restriction; PPROM, Preterm premature rupture of membranes; GH, Gestational hypertension; GDM, Gestational diabetes mellitus; OH, Overt hypothyroidism; HT, Hashimoto’s thyroiditis; ICP, Intrahepatic cholestasis of pregnancy
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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