Skip to main content
Fig. 4 | Reproductive Biology and Endocrinology

Fig. 4

From: In vitro fertilization with frozen embryo transfer increased histamine-mediated contractile sensitivity via PKCβ in human umbilical vein

Fig. 4

Functions of L-type voltage-dependent calcium channels and CAMK2 in histamine-induced vasoconstriction in HUV (A) The contractile responses to histamine with or without nifedipine (Nife, an L-type voltage-dependent calcium channel blocker, 10− 5 mol/L). (B) Bay K8644-mediated constriction in HUV. (C) The mRNA and protein expressions of CACNA1C. (D) The contractile responses to histamine with or without KN93 (a CAMK2 inhibitor, 10− 5 mol/L). (E) The mRNA expressions of CAMK2D and CAMK2G, and CAMK2D protein expression. Intra-group comparison, *, p < 0.05; ***, p < 0.001; ****, p < 0.0001. Inter-group comparison, ##, p < 0.01; ###, p < 0.001; ####, p < 0.0001

Back to article page

Reproductive Biology and Endocrinology

ISSN: 1477-7827

Contact us