Fig. 3
Functions of BKCa and KV channels in histamine-induced vasoconstrictions in HUV (A) The concentration response curves to histamine in the presence or absence of iberiotoxin (IbTX, a specific BKCa channels blocker, 10− 7 mol/L). (B) The concentration response curves to histamine in the presence or absence of 4-aminopyridine (4AP, a KV channel blocker, 10− 3 mol/L). (C-D) The mRNA and protein expressions of BKCa (α and β1). Inter-group comparison, #, p < 0.05