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Fig. 2 | Reproductive Biology and Endocrinology

Fig. 2

From: In vitro fertilization with frozen embryo transfer increased histamine-mediated contractile sensitivity via PKCβ in human umbilical vein

Fig. 2

Functions of H1R and H2R in histamine-induced vasoconstrictions of HUV (A) Histamine-induced constrictions in HUV in the presence or absence of diphenhydramine (PHR, an H1R inhibitor, 10− 5 mol/L). (B) Histamine-induced constrictions in HUV with or without famotidine (FA, an H2R inhibitor, 10− 5 mol/L). (C) Real-time records of doses of histamine or dimaprit-mediated vascular responses following 5-HT. (D) Real-time record of dimaprit-mediated vascular response in HUV. (E) The mRNA and protein expressions of H1R and H2R. Intra-group comparison, **, p < 0.01; ***, p < 0.001; ****, p < 0.0001. Inter-group comparison, ####, p < 0.0001

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