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Fig. 1 | Reproductive Biology and Endocrinology

Fig. 1

From: PIK3CA mutation in endometriotic epithelial cells promotes viperin-dependent inflammatory response to insulin

Fig. 1

Insulin treatment of endometriotic epithelial cells results in differential gene expression. A, Western blot of dose response of 12Z cells to insulin for phospho-AKT (Serine 473), AKT and β-Actin. Uncropped images are available in Supplemental Fig. 2. B, Volcano plot of DGE in 12Z cellstreated with 100 nM insulin vs. vehicle. FDR < 0.001 significant genes are red. C-D, GOBP enrichment among genes upregulated (C) or downregulated (D) following insulin treatment

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