Table 4 Reproductive outcomes of TSH < 2.98 group and TSH ≥ 2.98 group
From: Effect of TSH on oocyte maturation of PCOS patients with normal thyroid function in IVF
Parameter | TSH < 2.98 group (n = 454) | TSH ≥ 2.98 group (n = 141) | t/χ2 value | P value |
|---|---|---|---|---|
TSH (uIU/ml) | 2.06 ± 0.62 | 3.56 ± 0.41 | 716.78 | < 0.001*** |
Age (year) | 30.64 ± 3.09 | 30.41 ± 2.85 | 0.59 | 0.442 |
Infertility duration (year) | 3.39 ± 2.29 | 3.47 ± 2.10 | 0.13 | 0.713 |
AMH (ng/ml) | 10.58 ± 4.00 | 10.55 ± 3.89 | 0.009 | 0.926 |
Basal serum FSH (IU/L) | 6.26 ± 1.46 | 6.33 ± 1.55 | 0.25 | 0.613 |
Basal serum LH (IU/L) | 9.80 ± 11.60 | 9.66 ± 7.02 | 0.01 | 0.892 |
Basal serum E2 (pg/ml) | 44.57 ± 18.79 | 43.31 ± 20.30 | 0.42 | 0.514 |
Basal serum P (ng/ml) | 0.58 ± 0.39 | 0.57 ± 0.36 | 0.02 | 0.868 |
Basal serum T (ng/ml) | 0.61 ± 0.25 | 0.59 ± 0.28 | 0.58 | 0.444 |
Basal serum PRL (ng/ml) | 11.66 ± 6.24 | 12.69 ± 5.44 | 3.01 | 0.083 |
Antral Follicle Counting(AFC)) | 12.04 ± 3.98 | 12.65 ± 3.96 | 2.32 | 0.128 |
Height (cm) | 159.04 ± 5.41 | 158.89 ± 5.47 | 0.08 | 0.769 |
Weight (kg) | 61.39 ± 10.41 | 61.65 ± 9.27 | 0.06 | 0.792 |
Body Mass Index (kg/m2) | 24.25 ± 3.99 | 24.45 ± 3.75 | 0.26 | 0.605 |
Gn used dosage (IU) | 2278.91 ± 911.08 | 2235.69 ± 820.56 | 0.253 | 0.615 |
Gn used duration (d) | 11.65 ± 1.91 | 11.31 ± 1.81 | 3.50 | 0.062 |
FSH levels on HCG trigger day (IU/L) | 13.36 ± 4.80 | 13.80 ± 4.48 | 0.90 | 0.341 |
LH levels on HCG trigger day (IU/L) | 1.06 ± 0.84 | 1.03 ± 0.82 | 0.14 | 0.708 |
E2 levels on HCG trigger day (pg/ml) | 2747.72 ± 1157.98 | 2703.69 ± 1305.39 | 0.14 | 0.705 |
P levels on HCG trigger day (ng/ml) | 0.75 ± 0.43 | 0.76 ± 0.38 | 0.04 | 0.825 |
Endometrial thickness on HCG trigger day (mm) | 11.71 ± 2.61 | 11.71 ± 2.34 | 0.001 | 0.982 |
Number of oocytes retrieved | 11.02 ± 2.75 | 11.28 ± 3.10 | 0.92 | 0.336 |
Number of MII stage oocytes | 10.09 ± 2.72 | 9.91 ± 2.86 | 0.49 | 0.483 |
Oocyte maturation rate (%) | 91.7% | 88.2% | 10.86 | 0.001** |
2PN fertilization rate (%) | 84.61% | 84.48% | 0.01 | 0.914 |
Cleavage rate (%) | 99.51% | 98.96% | 3.73 | 0.054 |
Number of useable embryos | 4.24 ± 1.31 | 4.06 ± 1.34 | 2.02 | 0.156 |
Number of high-quality embryos | 3.21 ± 1.66 | 3.02 ± 1.69 | 1.33 | 0.249 |
High-quality embryo rate (%) | 71.1% | 69.0% | 0.63 | 0.426 |
Clinical pregnancy rate (%) | 64.3% (292/454) | 57.4% (81/141) | 2.17 | 0.085 |
Ectopic pregnancy rate (%) | 1.0% (3/292) | 0% (0/81) | 0.83 | 0.479 |
Early abortion rate (%) | 15.4% (45/292) | 17.3% (14/81) | 0.16 | 0.398 |
Live birth rate (%) | 53.7% (244/454) | 47.5% (67/141) | 1.67 | 0.116 |