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Table 1 Mean Maximal Inhibition Values for Vehicle and 17P.

From: Functional effects of 17alpha-hydroxyprogesterone caproate (17P) on human myometrial contractility in vitro

Myometrial Contractility Non-Pregnant Pregnant
  Net Vehicle Relaxation ± SEM Net 17P Relaxation ± SEM Net Vehicle Relaxation ± SEM Net 17P Relaxation ± SEM
Spontaneous -0.6% ± 12.1 (n = 6) 8.8% ± 11.0 (n = 6) 49.7% ± 11.9 (n = 6) 4.9% ± 7.2 (n = 6)
*Agonist-Induced 31.8% ± 5.0 (n = 6) -7.9% ± 6.5 (n = 6) 56.2% ± 2.3 (n = 6) 2.2% ± 1.3 (n = 6)
  1. *Phenylephrine-induced in non-pregnant myometrium and oxytocin-induced in pregnant myometrium.
  2. P = 0.022 in comparison to controls with PSS only
  3. P < 0.001 in comparison to controls with PSS only