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Table 2 Circulating hCG-sLHCGR in trisomic pregnancies

From: Quantitative ELISAs for serum soluble LHCGR and hCG-LHCGR complex: potential diagnostics in first trimester pregnancy screening for stillbirth, Down’s syndrome, preterm delivery and preeclampsia

Trisomy

hCGbetaMoM

PAPP-A MoM

NT MoM

T21 Risk

hCG-LHCGR Pmol/mL

T21

0.99

0.24

3.50

2.00

0.32

T21

1.66

0.25

2.60

2.00

1.16

T21

1.94

1.08

2.60

24.0

173.73

T21

0.91

0.34

4.10

2.00

1.42

T21

2.05

0.75

3.40

7.00

759.59

T21

1.27

0.50

2.90

3.00

0.58

T21

3.04

0.35

1.90

2.00

0.00

T21

2.12

0.27

4.00

2.00

252.89

T21

2.92

0.36

1.40

63.0

170.74

T21

3.23

0.20

6.40

2.00

0.00

T21

3.92

0.50

1.0

38.0

1.07

*T21

2.829

0.281

3.1

2.00

0.00

T21

0.71

0.22

NA

2.00

2.67

*T17

7.65

2.22

NA

19.00

0.00

T18

1.16

0.14

3.00

2.00

4.36

T18

0.25

0.27

5.80

66.0

1.45

T18

0.78

0.37

NA

2.00

79.37

  1. The multiplicity of median (MoM) for PAPP-A, hCGbeta, Nuchal translucency (NT), T21 risk are tabulated together with the hCG-sLHCGR concentrations. The ‘*’ and NA indicate live birth and data not available, respectively. T21, T17 and T18 are trisomy 21, 17 and 18, respectively.